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The 50 Best Acne Treatments for Combination Skin Rated on MIRA BEAUTY

The rankings for these drugstore acne treatments for combination skin are updated weekly. Shop with confidence & get the best price guaranteed.
EradiKate Acne Treatment by kate somerville

"Let me just begin by saying that I have struggled with acne for a little over 5 years. I’ve been to numerous dermatologists and I felt like I had tried everything. I started to feel so disheartened because I was spending $300+ a month on expensive prescriptions to help with my acne and they just weren’t working. Needless to say, I’ve learned that just because a product is more expensive, it does not make it more effective. Most of my face stays clear, but I have irritating and persistent acne along my chin, cheeks, and jaws. I happened to see this product while scrolling through the skincare products and praying to come across something worth the money. It was cheap enough and I decided to give it a try. I have now completely ditched my epiduo and some other expensive products, and use this as a spot treatment in its place. I have only been using it for about a week, but the results have been insane! Some of the pros: - it’s extremely quick drying. - you don’t have to worry about it rubbing off on and staining your sheets like you do with epiduo and some other spot treatments. - it works insanely quickly! Sleep with this on overnight and in the morning blemishes have either disappeared or diminished dramatically in size. - the price. Acne treatment can be ridiculously expensive. It’s so refreshing - especially for my wallet - to have something so effective and cheap. Well worth the money. - it doesn’t make your skin painfully dry or super red like many other treatments do. - it doesn’t react weird with other products. You don’t have to change anything else in your routine, this is easy to incorporate. I can not say enough about this product. I HIGHLY recommend this to all you guys and gals out there who struggle with persistent acne. Best spot treatment I’ve ever used." - sephora user

Blemish Correct Soothing Serum & Spot Treatment by Wabi-Sabi Botanicals

"This product is amazing. I am on my third bottle! I bought with the kit, and its unbelievable, I am 37 almost 38 and my skin is just awful : (, recently I had some weird small acne develop only on my chin, THEN once a month I had whatever life threw at me, then I had some weird bumps on the sides of my cheeks, oh yeah and WRINKLES had begun to set it, needless to say I was feeling pretty unattractive. I tried this as a last resort, and let me say, ITS WORTH EVERY PENNY. In the beginning it really felt like it tightened everything while immediately reducing acne. Now I use it everyday and night and haven't had any once a month breakouts and my skin looks amazing! Twice a week I do an exfoliate to keep the dead skins cells off and I did buy the night cream and day cream from skinceuticals if its starting to feel dry, but other than that I'm incredibly happy with this product! Only thing I'm missing is something to remove my makeup before starting this regimen. Less" - skinceuticals.com user

Special Clearing Booster by Dermalogica

Breakouts beware! Dermalogica's potent, topically applied benzoyl peroxide gel quickly dries existing blemishes.

AHA 7 Whitehead Power Liquid by cosrx

"WOW. I'll start by saying that I have dry, dehydrated skin with texture issues around my nose and cheeks and need constant exfoliation to avoid dry flakes. I rarely even get a pimple, but for some reason I had broken out with small, red comedones all over my cheeks and chin. After reading about different options, I decided to buy this. At night after cleansing, I applied it with a cotton pad, patting the product in as I was swiping. It burned... a lot. My whole face turned red, and I was worried that I had ruined my face forever! Fast-forward to the next morning... and literally all of the bumps had subsided- my cheeks were porcelain-smooth. The redness, both from the acne and the liquid had disappeared completely. My skin was completely toned and balanced. I cannot believe that this effect happened over one night, but this is my new miracle product. Although the brand is geared toward acne-prone types, I can see this product being beneficial toward all skin types because it is essentially an exfoliating peel. I also want to note that this has many similar ingredients to the famous (and much more expensive) Biologique Recherche Lotion P50, so I'm glad I found an affordable alternative! Less" - sokoglam.com user

PURE TRANSFORMATION Night Treatment by bareMinerals

A clear, powder night treatment formulated with Essential Mineral Complex, Indian gooseberry fruit extract, and ectoin to improve skin’s clarity and brighten.

Herbal Blemish Stick by Burt's Bees

"Continuous acne issues was NOT something I suffered from until my early 30's. Late bloomer I guess. Then breakouts were a daily event. The sides of my face stayed red and irritated because of acne. I tried the expensive stuff they sell at the high end places thinking price might represent how well they'd work on my acne. Tried organic lines (still expensive) hoping something would work and not leave my face dry. Tried the less expensive lines that require 4 or more steps. (not likely to stick to that but it was worth a shot) Changed my diet, drank more water, you name it, I tried it. I expected another fail from Burt's Bees but since it was easy to apply and inexpensive, I gave it a shot. My next step was going to be having a doctor explain if my post 30 hormones were out of whack. Burt's Bees acne stick has saved my face and my self image, which even at this age can take a hit. It doesn't leave any residue AT ALL and doesn't make my face feel dry or tight. The continuous acne is gone! The scent is...unique but not horrible. Almost like black licorice. I use it first thing every morning after I brush my teeth. And before I go to bed. It has worked so well that I keep one everywhere! Coworkers have seen me apply it after morning workouts and asked about the product. I can't say enough good things about it. Two of the ladies I work with have purchased it and have seen the same face saving results. When you find a product that works, you fall in love with it more and more each time you get to share its benefits to others needing the same results. Simple to use, convenient, and more importantly it's EFFECTIVE! <span class="shop__a pd-reviews__translate-span">« less</span>" - drugstore.com user

Effaclar A.I. Breakout Corrector by La Roche-Posay

"I bought this product around a month ago and it has very quickly become a firm favourite in my skin care routine, it is my new holy grail spot treatment and I know it will be a product I will repurchase again and again! I've used the product almost everyday since purchasing around a month ago and still have over 3/4 left, the tube is a fairly standard size for a spot treatment but works out to be very good value for money as a little goes a long way. The product itself is so different in comparison to all the other spot gels/creams/treatments I have tried in the past as it so gentle and yet so effective! I have combination skin t-zone skin that is also blemish prone around my chin area and I usually find that spots take forever to surface on my skin and then scar for a long time after. I also find that spots(whether treated or not) make my skin scab or crust over and most other treatments don't help, or even make it worse so when I stumbled across this after hearing good things about it, I had to try it. It doesn't really have much of a scent but also isn't completely unscented either, the texture is a combination of a gel and a light cream and a very small amount goes such a long way, I use this almost every day and whenever I feel a new blemish this erases and smooths skin to perfection within a day or 2 without it even reaching surface(if you catch it early enough) I cannot recommend this product enough to anyone and it is such a bargain for the quality of product too, can't wait to try out more products by this brand!!!! « less" - Escentual user

The Essentials Kit by mario badescu

"been using this only for a few days and i see a mayor difference already! the enzyme cleansing gel feels amazing on skin and a little goes a long way! i was a lit worried about the scent (i don’t have a good experience with perfumed cosmetics) but it’s very gentle and cleans skin nicely. silver powder is THE BOMB! i used it only once but my blackheads are nearly gone! it’s a bit tricky to use tho. the mask feels amazing, and leaves the skin super smooth. i have very sensitive skin (i’m usually red after using a mask) but no redness after this one! it’s a bit tricky to wash off and a bit messy on that matter, so i’d recommend taking it off in shower. drying lotion is AMAZING! we tried it at home for different types of acne and it worked like magic! + it’s full size product the rose water is not that amazing tho. smells a bit weird for my taste, and i feel like it makes my skin oily (but moisturised). the spray is a bit weak. OVERALL it is amazing, i use the seaweed cleanser lotion and cucumber makeup remover too and it’s honestly amazing. i’ll definitely purchase full sizes of every item here (maybe except the rose water)- but these small sizes are enough for a few months i think." - beautybay user

Natural Acne Solutions Pore Refining Scrub by Burt's Bees

"I have been using this product for a little over two years now, and I have nothing bad to say about it. I have EXTREMELY acne-prone, sensitive, and oily skin. (Just my luck, huh?) Virtually none of my skin was visible due to the amount of pustules I had. Being a, now 18 year old, teenager, this caused me to have a poor self-image, subsequently negatively affecting my overall confidence. I tried everything from Proactiv, to Clean & Clear, to prescription medicines, and nothing worked. Proactiv actually burned me and caused me to peel, which wasn't fun. Other products and cleansers helped slightly with the acne but did nothing for the redness. However, any progress I made from using the cleansers diminished in a matter of weeks. This pore refining scrub isn't abrasive or irritating, and always leaves my skin refreshed. I will admit there is what feels like a thin film left over, but it isn't anything that would make me change face washes. Even if you're reluctant due to the numerous complaints of the greasy residue left behind, this is definitely a product I'd recommend. <span class="shop__a pd-reviews__translate-span">« less</span>" - drugstore.com user

Clear Regular Strength Daily Skin Clearing Treatment With 2.5% Benzoyl Peroxide by Paula's Choice

"Clear is the appropriate name for this. My derma. gave me doxycycline for my huge cyst between my brows (reaction from another PC product SB BHA 2% Liq.) but turned out I was allergic because tiny red bumps appeared all over my face. She then prescribed 2.5% hydrocortisone cream which broke me out even more/worst(whiteheads/pustules/papules). Yes I lost my mind, nearly forgot about my huge cyst. But, this BP saved my entire face. Panicked by what's happened I use this against my derma's instructions which was to just stop the cream & use only gentle cleanser, no BHA's no BP's etc (good thing I bought a sample size before & had this on deck). I kept cleaning my face with my regular anti-bacterial cleanser not PC (I've been using since I was a kid & has been the only reason I have kept acne at bay). Then applied Olay Regenerist serum which I've also been using for years as my light moisturizer. I then spread this BP all over my face because I wanted to have a buffer between my clean skin & BP just in case I was allergic to it since this was my first time using it. I did this day & night & within a week my face was clear again. So thankful this BP worked in conjunction with my other 2 products I mentioned. It did dry out my skin but as soon I stopped using it when my face cleared, the dryness wasn't an issue anymore. Unexpectedly love this now & I still even have a little bit left in the sample size. My huge cyst is still there but my derma. will be chopping it off since (steroid injections didn't work on it). Will post review on that product next <span class="shop__a pd-reviews__translate-span">« less</span>" - Paula's Choice user

Potent-C Vitamin C Targeted Spot Brightener by Peter Thomas Roth

A potent dark spot treatment powered by vitamin C, vitamin E, ferulic acid, and advanced skin brightening actives.

Rapid Clear Acne Eliminating Spot Gel by Neutrogena

"I bought Neutrogena's Rapid Clear Facial lotion when I learned that moisturizing your face is a big step in combating acne. My acne cleared up with the use of this and the Rapid Clear cleanser, but I still love, love, love this lotion! It goes on very light, doesn't feel greasy at all, keeps my skin soft and moisturized all day without becoming oily, and works exceptionally well under makeup (isn't thick or clogging). I have oily skin, and finding the right lotion was a chore, but once I started using this Rapid Clear lotion, I was hooked. I've been using it for 3 years now, and the quality is still the same - great! You don't need a lot, it spreads well, and I cannot stress how light and great it feels! My skin is also sensitive, and this does not burn, sting, cause irritation or redness at all, like a lot of anti-acne products do! I adore this lotion, and religiously buy another one when I'm getting low. Overall, nothing negative to report, it's a fantastic lotion that works very well. :) <span class="shop__a pd-reviews__translate-span">« less</span>" - walmart.com user

Advanced Acne & Wrinkle Reducer by murad

A treatment for adult acne-prone skin, that clears and prevents acne and hormonal breakouts and Reduces the appearance of fine lines and wrinkles.

Clear Days Ahead Oil-Free Salicylic Acid Acne Treatment & Moisturizer by philosophy

"I have combo skin however am on the dryer side and tend to breakout if my skin gets too dry. After turning 30, I suddenly fell victim to acne which was so frustrating as I had not had this problem before. After getting it under control by using stronger, medicated treatment (Proactiv and Murad's Acne line), I decided to try this moisturizer/treatment. It works great! It's definitely on the gentler side however super effective. It's light, non-greasy, goes on slightly matte which is great under makeup and keeps my skin hydrated (if I'm dryer that day, I'll also wear Renewed Hope in a Jar). I would definitely recommend if you're looking for a gentle acne treatment...bonus that it's also a moisturizer." - Sephora user

Clear Complexion Treatment by boscia

Boscia's highly effective clear complexion treatment unclogs congested skin and prevents future breakouts. Purify, decongest, and refine pores for a clear complexion, without irritation. Formulated specifically for blemish-prone skin.

All-in-1 Acne Control Daily Scrub by Neutrogena

"From St. Ives to Biore to Clean and Clear to creams and gels-- I've tried them all and nothing, literally NOTHING has ever worked like Neutrogena All In 1 Acne Control. I have sensitive, combination skin and while my acne is not as bad as it was when I was say 14-17, it's still a good distance from "flawless". I wanted a face wash that would prevent/treat my acne, make my skin feel soft and of course thoroughly clean it and this product does all that and more. Because I had a lot acne in my early teens, and a compulsion for picking and popping pimples I have a lot of scars on my cheeks, chin and forehead. So when found a product that advertises fading acne scars I was excited but also really skeptical. I mean the ingredients look like that of any salicylic acid based acne product. Regardless, I took the risk and bought this and boy I am so glad I did. After about five years of searching I finally found a face wash that works. It doesn't leave my skin tight and flaky and it really does fade those acne scars. I've been using this for about four months now and I'm SO close to having smooth, flawless skin (I can be a little lazy with washing my face at times, I'm sure if I had more diligence my face would be akin to smooth leather or a baby's bum) My skin is smooth and soft to the touch and I have had a HUGE decrease in pimples. We're talking like one or two at most. It still surprises me how this face wash can simultaneously cut down on my oily areas while leaving the drier parts hydrated. And did I mention lack of acne scars?! Continuous use has evened out my skin tone substantially so I no longer have a need for foundation, seriously. While the things I mentioned above are all great, it just means that this is a product that's true to it's word. What makes it outstanding in my opinion is the fact that on top of actually working, it works pretty quickly too! Within 3 days of using this there was a noticeable difference in my skin. After about a week I had far less pimples. If I slip up and neglect to wash my face for sometime, or sleep with makeup I have no doubt that withing 1-3 days my face will be back on track. Oh and it lasts pretty long too! Four months later and I'm still on ym first bottle, lol. I genuinely can't say anything bad about this product. I know everyone's skin is different but I've realized that most people either do well with salicylic acid or benzoyl peroxide products so if you're one of the former, or if you have sensitive skin, look no further! The answer to all your acne/facial skin problems is right here :-) <span class="shop__a pd-reviews__translate-span">« less</span>" - Target user

African Black Soap Acne Care Kit by SheaMoisture

"Talk about refreshing, this impressed me. I spend a lot on face products and have tried many brands and this by far was the most compatible with my skin. I first purchased the mask, and though when you apply it it feels as though nothing is happening. I woke up with pimples that were significantly reduced in size. Actually before trying out the product I had three large pimples on my face, and I could just tell by the end of the week they will almost be gone. The soap wasn't drying, but if you use more soap to wash off your face it can become drying.In addition, it doesn't take off eye makeup, but that was a minor issue to me. Lastly, the moisturizer took me by surprise. The first time I washed my face with the soap i over did it because I had foundation prior to using it so my face was dry, but not tight. I applied the moisturizer on after washing with the soap and just wow, it really penetrated into my skin leaving it hydrated, but not oily, with a matte finish. Not a dry matte but just right. If you are on the fence about buying the full size of the system just buy the set, it is worth trying. After years of trying out products I think this is the one. Also the products in the kit feel very gentle, but are super effective. « less" - Target user

Fearless Clear Skin And Acne Kit 14 Daily by Sephora Collection

"I am 33 and I had suffered from adult acne for the past three years. Before that, I never ever had pimples. I think the cause of it was mainly excessive work stress and poor diet. (Just to picture you my background...I lost over 10 pounds when I was already less than 100 pounds...and I am 5'7. I was working 90 hours a week at some points and barely slept during the three years. No joke.) I visited dermatologist first time in my life and took the antibiotics twice but it always came back once I finished the cycle of the pills... My face was covered by red and white acne and I felt super depressed by just looking at myself. I decided to take more affirmative action. I changed my job to reduce the horrible daily stress. But the acne still stayed and got even worse. I started eating more properly and gained back the lost weight. I did some research to improve my gut health through the diet. Then I came across this Daily Cleanse. I was worried about my liver health as well because I was drinking everyday when I was at the previous job and the habit stayed with me even I switched to a new, better job. I decided to give a try to this supplement. And that was the best decision I ever made. One week in after starting taking the supplement, I saw some flaring up on my face and neck, but then it calmed down. (To note I was having my period during the first week.) Every morning I felt less and less insecure to look at myself in the mirror. I am almost done with the first bottle, so I ordered two more bottles. I now drink less and take some additional probiotic product as well so I cannot say it's all because of this product, but it did contribute to the fact that now I can go out without any makeup to run my errands, or go out without applying concealer! I can't thank enough to HUM<3 « less" - Sephora user

Hyaluspot Fast Acting Anti Imperfections Targeted Care No by vichy

"I received this product free to try from glam sense. I know I likely wouldn't buy this line of products without being able to sample it first as it is high quality and comparable in price to high end competitors. I'm so glad I was chosen to test this because it truly is amazing. I noticed results in my complexion within 48 hours. Reduced appearance of pores, pimples, and added a general healthy glow to my skin. A tiny drop goes a long way. I am in love without Vichy products now....non-drying, great for sensitive skin as well as combination skin, light, fresh scent, and the list goes on and on! I use it regularly now with the foam cleanser and the night detox and this combo keeps my skin clear and bright! Love it! Thanks so much, Vichy! Keep doing what you're doing" - vichy.ca user